By Kyle Green ‘14 and Meewon Park ‘14, THURJ Staff George Daley: A Pioneer in Stem Cell Research In recent years, the advances made in stem cell research have astounded even the greatest minds in the field. George Daley, Professor of Hematology at Harvard Medical School and Director of the Stem Cell Transplantation Program at HMMI/Children’s Hospital Boston, said, “I [...]
Hemojuvelin (Hjv) is a member of the repulsive-guidance molecule (RGM) family that upregulates transcription of the iron regulatory hormone hepcidin by activating the bone morphogenetic protein (BMP) signaling pathway in mammalian cells. Hepcidin has been called the master regulator for iron, and hepcidin expression and regulation deviations have been implicated in disease such as juvenile hemochromatosis and thalassemia. This paper evaluates the effects of hjv on hepcidin expression in embryonic zebrafish development.
This paper evaluates the impact of the National Basketball Association (NBA)’s soft salary cap and luxury tax system, and showed that talent and payroll are linked within the league, causing unbalanced team competitiveness.
By Ina Chen ‘14 and Jonathan Zhou ‘14, THURJ Staff It is common knowledge that mental abilities decrease with age. Over the years, many people have attempted to understand the processes of aging and develop methods to delay the debilitating conditions brought on by old age. Recently, advancements in the field of biology have revealed more and more about the [...]
Among the most recent and extremely successful global health initiatives is a seemingly obscure organization that took root in the hallways of Harvard Medical School laboratories almost ten years ago—Seeding Labs.
With the rise of the field of genetics, our genes and the environment we grow up in became polarized forces, competing determinants of who we are. Ongoing scientific research, however, continues to illuminate the fact that they are not two opposing forces; instead, they continuously interact as they drive the development of living organisms.
What separates apes from humans? What causes some people to doubt their own existence? Why can some associate colors with numbers while others associate them with musical notes? Dr. Vilyanur S. Ramachandran seeks to probe the inner workings of the human brain in his new book, The Tell-Tale Brain: A Neuroscientist’s Quest for What Makes Us Human.
An analysis of methods for detecting tacit collusion in FCC spectrum auctions.
Angelman syndrome (AS) is a severe neurological disorder often involving epilepsy, autistic tendencies, mental retardation and ataxia. The genetic locus of the disorder has been identified as an inability to inherit a functional maternal copy of the gene UBE3A, which encodes for a ubiquitin ligase involved in proteasome-mediated degradation. Here, Zapf and Anderson characterizes the effect of Ube3a on tissue development.
